Share Course Ware
Natural Sciences > Chemistry > Synthetic Organic Chemistry II
 Synthetic Organic Chemistry II  posted by  member7_php   on 2/12/2009  Add Courseware to favorites Add To Favorites  
Further Reading
More Options

Danheiser, Rick, 5.512 Synthetic Organic Chemistry II, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), (Accessed 09 Jul, 2010). License: Creative Commons BY-NC-SA

Spring 2005

Oxazaborolidine-catalyzed asymmetric reduction of ketones. (Figure courtesy of OCW.)

Course Highlights

This course features a complete set of assignments and a series of lecture note outlines.

Course Description

This course focuses on general methods and strategies for the synthesis of complex organic molecules. Emphasis is on strategies for stereoselective synthesis, including stereocontrolled synthesis of complex acyclic compounds.


Course Texts

Lecture Notes: Methods for the Asymmetric Synthesis of Complex Organic Molecules, Daniel J. O'Leary, Associate Professor of Chemistry, Pomona College (2001).


Course grades will be based on two exams scheduled during the semester. There is no final exam.


1 Strategies for Stereocontrolled Synthesis I Problem set 1 due
2 Strategies for Stereocontrolled Synthesis II  
3 Strategies for Stereocontrolled Synthesis III  
4 Strategies for Stereocontrolled Synthesis IV  
5 Strategies for Stereocontrolled Synthesis V Problem set 2 due
6 Strategies for Stereocontrolled Synthesis VI  
7 Stereocontrolled Alkylation I  
8 Stereocontrolled Alkylation II  
9 Stereocontrolled Alkylation III Problem set 3 due
10 Stereocontrolled Alkylation IV  
11 Stereocontrolled Conjugate Addition I  
12 Stereocontrolled Conjugate Addition II Problem set 4 due
13 Stereocontrolled Conjugate Addition III  
  Exam I  
14 Stereocontrolled 1,2 Addition to Carbonyls I  
15 Stereocontrolled 1,2 Addition to Carbonyls II  
16 Addition of Allylmetals to Carbonyls I  
17 Addition of Allylmetals to Carbonyls II  
18 Addition of Allylmetals to Carbonyls III Problem set 5 due
19 Stereocontrolled Aldol Reactions I  
20 Stereocontrolled Aldol Reactions II  
21 Aldol Reactions III and Stereocontrolled Carbonyl Reduction Problem set 6 due
22 Stereocontrolled Carbonyl and Alkene Reduction  
23 Stereocontrolled Alkene Reduction and Hydroboration  
24 Stereocontrolled Dihydroxylation and Epoxidation I Problem set 7 due
25 Stereocontrolled Epoxidation II  
  Exam II   Tell A Friend