Ma, Hongshen, 2.996 Biomedical Devices Design Laboratory, Fall 2007. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed 07 Jul, 2010). License: Creative Commons BY-NC-SA
Biomedical Devices Design Laboratory
Fall 2007

Engineering in the biomedical field can take many forms, such as designing portable devices like a blood glucose meter, or larger-scale machines such as surgical robots. (Image by MIT OCW).
Course Description
This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six weeks are in support of the project. Major team-based design, build, and test project in the last six weeks. Student teams will be composed of both electrical engineering and mechanical engineering students.
Technical Requirements
Special software is required to use some of the files in this course: .exe, .mov, .h, .c, .cml, .psl, .ssl, .pcb, .sch, .ept, and .zip.
Syllabus
Course Description
This course provides intensive coverage of the theory and practice of electromechanical instrument design with application to biomedical devices. Students will work with MGH doctors to develop new medical products from concept to prototype development and testing. Lectures will present techniques for designing electronic circuits as part of complete sensor systems. Topics covered include: basic electronics circuits, principles of accuracy, op amp circuits, analog signal conditioning, power supplies, microprocessors, wireless communications, sensors, and sensor interface circuits. Labs will cover practical printed circuit board (PCB) design including component selection, PCB layout, assembly, and planning and budgeting for large projects. Problem sets and labs in the first six Weeks are in support of the project. Major team-based design, build, and test project in the last six Weeks. Student teams will be composed of both electrical engineering and mechanical engineering students.
Teaching Staff
Instructor: Dr. Hongshen Ma
Course Administrator: Maureen Lynch
Mechanical Guru: Prof. Alexander H. Slocum
Electrical Guru: Dr. Chris Salthouse
Medical Guru: Dr. Rajiv Gupta
Grading
Grading criteria.
ACTIVITIES |
PERCENTAGES |
Assignments and labs |
40% |
Team project |
60% |
Assignments and Labs
There will be three assignments covering these lecture areas:
- Assignment 1: Impedance analysis
- Assignment 2: OpAmp circuits
- Assignment 3: Sensors and signal processing
There will be one lab designed to lead students through the process of designing, fabricating, and assembling a printed circuit board (PCB). Students will create a multipurpose data acquisition system that includes a microprocessor, USB connectivity, and wireless connectivity. The labs are done individually, which means that each student will have the opportunity to make their own PCB. The PCB created in the lab will be useful in the project. The lab will require approximately half of the semester to complete and will be composed of the following 6 parts:
- Lab 1: Circuit design and component selection
- Lab 2: Learn to use PCB Artist, generate libraries, create schematic
- Lab 3: PCB layout
- Lab 4: PCB assembly
- Lab 5: Microprocessor programming
- Lab 6: PC user interface design using Visual Basic® (optional)
Team Project
Students will attend a special lecture two days before Lec #2, where doctors from MGH will present their problems and needs for new medical devices. Students will self-organize into teams of four and each team will select a particular problem on which they would like to work. An approximate schedule for the project is given in the course schedule. Starting in Week 3, the teams will meet weekly with staff. Each sponsoring doctor will also be available to meet with the team on a weekly basis. From Week 7 onwards, each team will make weekly presentations on their progress. There will also be a final presentation and demonstration of their device to the MGH doctors in the last Week. A detailed write-up of the project results in the format of a journal article (20 pages double spaced plus figures. Details go in Appendices) is required. An "A" grade project is one that is presented in form and content that is ready to be submitted to a peer-reviewed journal.
Each team will have a budget of $3000 to prototype and test their solution. Legitimate expenses include mechanical and electronic components, PCB fabrication, machine shop and rapid prototyping services (must get an estimate for cost of job), local travel (mileage), etc. (ask Maureen Lynch, Hong Ma, or Prof. Slocum if in doubt). Maureen Lynch will administer team accounts. There is lab space set aside for each team in 5-007.
A key part of your project is to record what you did to help you organize your thoughts and also allow others (or yourself) to continue the work after the semester. Therefore, it is critical to write-as-you-go. Otherwise, brilliant ideas will be lost and may never be reformulated again.
Calendar
Course schedule.
WEEK # |
TOPICS |
KEY DATES |
1 |
Lab 1 and 2 distributed |
|
Lecture 1 - Introduction |
|
2 |
Doctors present ideas in class
Lab 1 and 2
Design custom circuit, learn PCB artist, generate libraries, create schematic
|
Project goals
Students form teams of 4
|
Lecture 2 - Basic electronics
Linear elements, thevenin-norton, impedance analysis
|
|
3 |
Lecture 3 - Diodes and transistors
Models, LEDs, peak-detector, zeners, diode protection circuits, BJT, FET, amplifiers, drivers, H-bridges
Lab 3
Layout PCB
|
Lab 1 and 2 due
Project goals
Define functional requirements
Define components of the system
Research strategies by literature and patent review
|
Lecture 4 - Power supplies
Proper bypassing, linear power supplies, switching power supplies
MIT libraries lectures on literature and patent searching
|
Lab 3 due; submit PCB for manufacturing |
4 |
Lecture 5 - Microprocessors I
Basic topologies, feedback, stability, accurate peak detector
|
Project goals
Identify most critical module (MCM)
Develop bench level experiments to test strategies for the MCM
Begin to acquire components for MCM and other modules
|
5 |
Lecture 6 - Microprocessors II
Practical considerations, reading op amp datasheets error propagation, filters
Lab 4
Soldering, assembly, and debugging
|
Project goals
Run bench level experiments
|
Lecture 7 - OpAmps I
Basics programming concepts, memory organization, clocks, ADCs
|
Lab 4 due |
6 |
Lab 5
Microprocessor programming
|
Project goals
Design circuits for MCM
|
Robopsy guest lecture |
|
7 |
Lecture 8 - OpAmps II
Timers, communications, wireless
|
Project goals
Design circuits for other modules
Layout circuits
Submit for manufacturing
|
Lecture 9 - Analog signal processing
ADC, references, noise, synchronous detection
|
Lab 5 due |
8 |
Lecture 10 - Sensors I
Capacitive, impedance, optical
Lab 6 (optional)
PC user interface design in Visual Basic®
|
Project goals
Assemble and test first iteration
|
Lecture 11 - Sensors II
Encoders, magnetic, strain acoustic, inertial
|
Lab 6 due |
9 |
Chris Salthouse guest lecture |
Project goals
Assemble and test first iteration
|
No lecture, weekly team meeting with staff |
|
10 |
No lecture, weekly team meeting with staff |
Project goals
Design circuits for 2nd iteration
|
11 |
No lecture, weekly team meeting with staff |
Project goals
Submit for final manufacturing
|
12 |
No lecture, weekly team meeting with staff |
Project goals
Develop software and firmware
|
13 |
No lecture, weekly team meeting with staff |
Project goals
Integration and test device
|
14 |
No lecture, weekly team meeting with staff |
Project goals
Prototype complete, final paper done
|
Final presentations in class: projects 1 and 2 |
|
15 |
Final presentations in class: projects 3 and 4 |
|
Final class: turn in journal article as final paper
Recap and reflections
|
Final papers will be accepted as late as last class |
|
|