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 A Hands-On Introduction to Nuclear Magnetic Resona  posted by  member150_php   on 2/26/2009  Add Courseware to favorites Add To Favorites  
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Abstract/Syllabus:

Cory, David, 22.920 A Hands-On Introduction to Nuclear Magnetic Resonance, January IAP 1997. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed 07 Jul, 2010). License: Creative Commons BY-NC-SA

A Hands-On Introduction to Nuclear Magnetic Resonance

January (IAP) 1997

A picture of an animation in the 22.920 animations section.
Image taken from an animation in the 22.920 animations section. (Courtesy of Prof. David Cory.)

Course Highlights

The aim of this short course is to present a physical picture of the basic principles of Nuclear Magnetic Resonance (NMR) spectroscopy and imaging, along with a brief introduction to selected experimental details. A full set of lecture notes (with animations) and lab exercises is included.

Course Description

Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging.

Technical Requirements

QuickTime Player software is required to view the .movie files found on this course site.

Syllabus

Abstract 

The course provides an introduction to NMR for those who wish to have a background in both the classical theory and in the instrumentation. The course will be run as a series of 8 lectures, each of which will be followed be laboratory experiments to demonstrate the ideas that were presented during the lecture and to familiarize students with state of the art NMR instrumentation. The experiments will cover topics ranging from spin dynamics, to spectroscopy and will include imaging.

Outline

LEC# 1
Nuclear Spin and Magnetic Resonance.

LEC# 2
The Rotating Frame, RF Pulses and the Bloch's Equations.

LEC# 3
Magnetic field gradients, k-space and Diffusion

LEC# 4
Gradient and Spin Echoes

LEC# 5
NMR Imaging in 2D, Slice Selection

LEC# 6
More Imaging, and Flow Studies

LEC# 7
NMR spectroscopy, Chemical Shifts, Spin-Spin Couplings

LEC# 8
Two Dimensional NMR Methods, the COSY Experiment

Calendar
 

LEC #

     

TOPICS

     

LECTURE NOTES

     

EXPERIMENTS

 

 

1

     

General Introduction to Magnetic Resonance

     

     

 

 

2

     

Bloch's eqn.; Rotating Reference Frame; RF Pulses

     

     

 

 

3

     

Magnetic Field Gradients, k-space Diffusion

     

     

 

 

4

     

Spin Echoes; Hahn Echo; 90 - 90 echo; Stimulated Echo

     

     

 

 

5

     

NMR Imaging; 2D Images; Slice Selection

     

     

 

 

6

     

More Imaging; Spin Echo vs Gradient Echo; Resolution; Flow

             

 

 

7

     

Spectroscopy; Chemical shifts; Couplings; Assignments

             

 

 

8

     

2D Spectroscopy, and the COSY Experiment

               

 




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